Risk guides
Understand the scores before you act on them
Every calculator in Vitals comes from a published model. These guides explain what each one measures, what the numbers mean and where each model stops being reliable.
ASCVD 10-year risk: what the Pooled Cohort Equations tell you
How the ACC/AHA Pooled Cohort Equations estimate your 10-year risk of heart attack or stroke, which inputs matter, and what the risk bands mean.
QRISK3 explained: a broader cardiovascular risk model
What QRISK3 measures, the extra conditions it accounts for that older calculators ignore, and how to interpret your 10-year percentage.
Fracture risk: how FRAX-style bone scores work
How 10-year major osteoporotic and hip fracture probabilities are estimated, which clinical risk factors count, and when a DXA scan changes the answer.
eGFR and CKD-EPI 2021: reading your kidney numbers
How the CKD-EPI 2021 creatinine equation estimates kidney function, what the G-stages mean, and which everyday medications need a second look.
HOMA-IR: measuring insulin resistance before diabetes appears
How HOMA-IR is calculated from fasting glucose and insulin, what the thresholds mean, and how it relates to HOMA-B, QUICKI and the TyG index.
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